Search results for "Critical parameter"
showing 6 items of 6 documents
Use of the Cultex® Radial Flow System as an in vitro exposure method to assess acute pulmonary toxicity of fine dusts and nanoparticles with special …
2013
Exposure of the respiratory tract to airborne particles (including metal-dusts and nano-particles) is considered as a serious health hazard. For a wide range of substances basic knowledge about the toxic properties and the underlying pathomechanisms is lacking or even completely missing. Legislation demands the toxicological characterization of all chemicals placed on the market until 2018 (REACH). As toxicological in vivo data are rare with regard to acute lung toxicity or exhibit distinct limitations (e.g. inter-species differences) and legislation claims the reduction of animal experiments in general ("3R" principle), profound in vitro models have to be established and characterized to m…
Analysis of an interferometric optical fibre detection technique applied to silicon vibrating sensors
1987
A simple and accurate analysis of a single-mode optical fibre interferometric displacement detection technique is resented. This analysis is in good agreement with experimental measurements, and shows that angular alignment between the fibre and the sensor is the most critical parameter.
The rheological behavior of HDPE/LDPE blends 4. Instability phenomena in capillary flow
1984
Experimental data, relative to instability phenomena in capillary flow, have been collected for HDPE/LDPE blends already characterized from a rheological viewpoint. The data comprise morphological observations as well as the determination of critical parameters as a function of the blend composition and of the processing conditions.
A Review of the Current Knowledge of Thermal Stability of Anthocyanins and Approaches to Their Stabilization to Heat
2021
Anthocyanins are colored valuable biocompounds, of which extraction increases globally, although functional applications are restrained by their limited environmental stability. Temperature is a critical parameter of food industrial processing that impacts on the food matrix, particularly affecting heat-sensitive compounds such as anthocyanins. Due to the notable scientific progress in the field of thermal stability of anthocyanins, an analytical and synthetic integration of published data is required. This review focuses on the molecular mechanisms and the kinetic parameters of anthocyanin degradation during heating, both in extracts and real food matrices. Several kinetic models (Arrheniu…
Evaluation of advanced silica packings for the separation of biopolymers by high-performance liquid chromatography
1989
Abstract The linear solvent strength model of Snyder was applied to describe fast protein separations on 2.1-μm non-porous, silica-based strong anion exchangers. It was demonstrated on short columns packed with these anion exchangers that (i) a substantially higher resolution of proteins and nucleotides was obtained at gradient times of less than 5 min than on porous anion exchangers; (ii) the low external surface area of the non-porous anion exchanger is not a critical parameter in analytical separations and (iii) μg-amounts of enzymes of high purity and full biological activity were isolated.
Heterogeneous Oxygenation of Rectal Carcinomas in Humans: A Critical Parameter for Preoperative Irradiation?
1984
The surgical treatment of rectal carcinoma in humans is often combined with irradiation. However, the efficacy of this latter treatment modality is crucially influenced by the oxygenation status of the tumor tissue to be treated. Therefore, the knowledge of the O2 supply to the tumor tissue is a decisive prerequisite for the assessment of the efficiency of radiotherapy.